Polynucleotide treatments cater to a diverse range of skin issues and conditions, leveraging their unique biological properties for effective results:

  • Reducing Ageing Signs: These treatments directly target common ageing signs like wrinkles, fine lines, and skin sagging.They stimulate collagen and elastin production, essential for maintaining skin firmness and elasticity.
  • Enhancing Skin Hydration and Texture: Polynucleotides significantly boost skin hydration and improve overall texture.They enhance the skin’s moisture retention capabilities, resulting in a plumper and smoother appearance.
  • Promoting Skin Rejuvenation and Regeneration: The treatments excel in rejuvenating and regenerating skin cells. They are particularly beneficial for skin that has suffered environmental damage, aiding in repair and renewal.
  • Addressing Scarring and Hyperpigmentation: Polynucleotides effectively reduce the appearance of scars, including those from acne, and help even out skin tone. They work on reducing hyperpigmentation, leading to a more uniform skin complexion.
  • Improving Skin Elasticity: The treatments contribute to enhanced skin elasticity. This benefit is especially noticeable in areas prone to elasticity loss, such as the under-eye region and neck.
  • Treating Sun-Damaged Skin: Polynucleotides are adept at treating sun-damaged skin, mitigating some effects of UV exposure. They improve skin texture and reduce the visibility of sunspots.
  • Revitalising Overall Skin Health: Beyond targeting specific issues, polynucleotide treatments offer holistic skin revitalisation.They improve the overall health and vitality of the skin, contributing to a rejuvenated appearance.


What are polynucleotides?

Polynucleotides in the simplest of terms are injectable, sterile and highly purified products, derived from fish, typically salmon or trout.  The polynucleotides are then incorporated into a polymerised injectable gel, which once injected binds with water molecules to make skin tissue firmer and more hydrated.

Some people refer to them as “biostimulators” because the polynucleotide chain has an anti-free radical action and serves as a scavenger of hydroxyl radicals, which accumulate due to stress and UV radiation (sun damage)The hydration and anti-free radical properties of polynucleotides help to create the optimal environment for fibroblast growth, responsible for generating collagen, elastin, and hyaluronic acid, essential for resilient skin.

How do polynucleotides differ to injectable skin boosters, like Profhilo?

Polynucleotides and injectable skin boosters have similar effects, but rather than merely hydrating, like hyaluronic acid skin boosters such as Profhilo, polynucleotides actively signal cells to produce collagen and elastin. They address areas where many skin boosters cannot, such as the eyes, lips, and forehead.

Where are polynucleotides typically injected?

Polynucleotides can be effectively used for various facial areas including under the eyes, neck, and even the jawline and cheekbones. Currently, the most sought-after application tends to be the under-eye area.

The introduction of polynucleotides for under-eye treatment is revolutionising cosmetic procedures. There are a lot of clients who are concerned about their under-eye area and wouldn’t qualify for tear-trough filler due to under-eye bags or tissue elasticity issues, but thanks to polynucleotides, they can significantly improve this area.

Additionally, for individuals already receiving tear-trough filler for hollowing, incorporating polynucleotides into the treatment plan often allows for longer intervals between filler sessions.

Who are suitable candidates for polynucleotide treatments?

Polynucleotide contains animal-derived ingredients, making it unsuitable for vegetarians, vegans, or individuals with fish allergies. Additionally, it is not recommended during pregnancy or while breastfeeding, as is the case with any injectable procedures.  However, due to its natural composition and versatility in application, it will be suitable for most clients.

What do polynucleotides treatments involve?

Polynucleotides treatment typically involves two to three sessions, spaced approximately two to four weeks apart, depending on the clients needs. Before administering the injections, a local anaesthetic cream to numb the area will be applied, and then the product will be injected into the targeted area of the face or neck.

For under-eye treatments, I tend to avoid using needles and opt for a blunt-tipped cannula inserted through a single point in the cheek. This technique helps minimise bruising and swelling in the area. But for crows feet, a few blebs of product just under the skin work better, using a tiny mesotherapy needle. The procedure itself is relatively quick, and although there may be some discomfort during the injections, most clients tolerate it well.

When do you see the results of polynucleotides, and how long do they last?

Clients will begin to notice results quite soon after the initial session, but the second session jumpstarts the remodelling process. The product continues its effects for the first 12 weeks, progressively improving over time. However, clients will experience an early improvement and lift after the first session. Typically, the effects of polynucleotide treatments last for approximately six months before requiring a maintenance session.

Can you combine polynucleotides with other cosmetic treatments?

Polynucleotides are versatile, and compatible with various energy-based treatments. They address concerns such as dark circles, under-eye hollowing, and crepey skin around the eyes. Although polynucleotides can be used alongside dermal fillers, I have to stress the importance of individualised treatment plans. Some adopt a sequential approach, preferring to address significant hollowing under the eyes with tear-trough filler initially and then introducing polynucleotides to enhance skin quality. It is crucial to evaluate the clients needs during the consultation, to tailor their treatment plans and to ensure realistic goals and safe, effective outcomes.

What are the risks associated with injectable polynucleotides?

Common risks linked to polynucleotide treatments may include bruising and swelling.

How much do polynucleotides treatments cost?

It depends on the area(s) needing treatment, to how much product is needed. Typically 1ml is needed for the eye area, and 2ml is needed for the face, neck OR a small part of the body, per session. Usually 2-3 treatments are needed to complete the treatment, spaced 2-4 weeks apart.

Per session:

1ml Vitaran Polynucleotides £175 (under eyes)

2ml Vitaran Polynucleotides £250 (face, neck or body)